Lyme Disease Total Antibodies with Reflex to Confirmatory Immunoassay, Serum
| Abbrev Code: | LYMEGM | ||
| Order Code: | LAB6417 | Order Name: | Lyme Disease Total Antibodies with Reflex to Confirm IA |
| Synonyms: | Lyme Borreliosis Antibodies; Borrelia burgdorferi Antibodies; LYMEGM | ||
| Methodology: | Chemiluminescent immunoassay | ||
| CPT Codes: | 86618 x1, 86618 x1 | ||
| Test Includes: | Total antibody detection to Borrelia burgdorferi with confirmation by chemiluminescent immunoassay at an additional charge. | ||
| Turnaround Time: | Performed Mon-Fri; results are reported the same day. | ||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 3 mL |
| Minimum\Peds Volume: | 1 mL |
| Container: | Red or gold (gel) Alternate Containers: Green (lithium heparin, gel), Purple (EDTA), Red (no gel) |
| Causes for Rejection: | Grossly hemolyzed, icteric or lipemic samples; samples containing particulate matter or obvious microbial contamination; CSF. |
Processing and Shipping
| Specimen Processing: | Centrifuge and aliquot 1.5 mL, 0.4 mL minimum. Store in refrigerator up to 7 days. |
| Shipping Instructions: | Ship refrigerated (no more than 7 days) or frozen. |
| Stability: | Specimens should be maintained at 2-8°C for no more than 7 days from sample collection; otherwise they should be stored frozen at -20°C or below and shipped on dry ice. |
| Test Performed at or Referral Lab | UM Specialty Core/Prot/Endo (Liaison D) |
Interpretive
| Reference Range: | Reported as negative, equivocal, or positive. Equivocal or positive samples are confirmed by immunoassay.
Lyme Disease Antibodies
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| Limitations: | Patients may be serologically negative during the early stages of the disease. Potential assay interference due to circulating antibodies in patients with Human Ehrlichiosis (HGE) and Tick-Borne Relapsing Fever (TBRF), Babesiosis, Parvovirus, and EBV infections have been found. Interpret results from these patients with caution. | ||||||
| Use: | Diagnosis of Lyme disease in conjunction with clinical manifestations. Borrelia burgdorferi IgM and IgG antibodies are usually present within 1-3 weeks after disease onset. |
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