MDA5 Antibody
| Abbrev Code: | ARMISC | ||
| Order Code: | LAB4909 | Order Name: | Send Outs Misc Test |
| Synonyms: | anti MDA5; anti-MDA5; CADM 140 | ||
| Methodology: | Enzyme linked immunosorbent assay (ELISA) | ||
| CPT Codes: | 83520 x1 | ||
| Turnaround Time: | Specimens are sent to the reference laboratory Mon-Sat; results are reported within 9 days. | ||
| Compliance: | This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration. |
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Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2.2 mL |
| Minimum\Peds Volume: | 0.8 mL. Does not permit repeat analysis. |
| Container: | Red or gold (gel) Alternate Containers: Red (no gel) |
| Causes for Rejection: | Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types. |
Processing and Shipping
| Specimen Processing: | Within 1 hour of collection centrifuge and aliquot 1 mL; 0.3 mL minimum. Store in refrigerator. |
| Shipping Instructions: | Ship at refrigerated temperature. |
| Stability: | 7 days room temperature; 14 days refrigerated; 60 days frozen |
| Test Performed at or Referral Lab | Lab Sendouts (LabCorp via ARUP) |
| Referral Lab number: | 520002 |
Interpretive
| Reference Range: | By report. |
| Use: | Anti-MDA5 antibodies are present in 7-35% of adult Dm. Features consist of absent or mild muscle symptoms (CADM), associated with rapidly progressive ILD, specific mucocutaneous features of skin ulcerations and papules, higher risk of oral ulcerations and arthritis. |
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