Scleroderma (Scl-70) (ENA) Antibody, IgG
Abbrev Code: | SCLIGG | ||
Order Code: | LAB6367 | Order Name: | Scleroderma AB (Scl-70) (ENA) IgG |
Synonyms: | SCL-70; Antitopoisomerase-1; Anti-Scleroderma Antibody | ||
Methodology: | Fluorescent enzyme immunoassay | ||
CPT Codes: | 86235 x1 | ||
Turnaround Time: | Performed twice weekly; results are reported within 4 days. |
Collection Instructions
Specimen: | Blood |
Optimal Volume: | 2 mL |
Minimum\Peds Volume: | 0.9 mL |
Container: | Red or gold (gel) Alternate Containers: Green (lithium heparin, gel), Purple (EDTA), Red (no gel) |
Causes for Rejection: | Gross hemolysis |
Processing and Shipping
Specimen Processing: | Centrifuge and aliquot 1 mL, 0.35 mL minimum. Store in refrigerator up to 14 days. |
Shipping Instructions: | Ship at refrigerated temperature. |
Test Performed at or Referral Lab | UM Specialty Core/Prot/Endo (Phadia ELiA G) |
Interpretive
Reference Range: |
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Use: | Scleroderma (Scl-70) antibody is seen in 20-60% of patients with scleroderma and is considered diagnostic and specific for scleroderma if it is the only ENA antibody present. Scl-70 is also seen in approximately 25% of progressive systemic sclerosis (PSS). |
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