Heparin Unfractionated Anti Xa Level
| Sunquest Code: | AAUFH | ||
| Epic Code: | LAB8132 | Epic Name: | Heparin Unfractionated Anti Xa Level |
| Synonyms: | Heparin Xa; Heparin Level; Anti 10A; Anti Xa; UFH Anti 10A Level; UFH Anti Xa Level | ||
| Methodology: | Chromogenic (synthetic substrate) activity assay | ||
| Turnaround Time: | Performed and reported 24 hours/day | ||
| Associated Links: | Specimen Collection and Processing for Coagulation Specimens |
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Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2.7 mL (in 3 mL tube) - filled to fill line on the tube. |
| Minimum\Peds Volume: | 1.8 mL (in 2 mL tube) - filled to fill line on the tube. |
| Container: | Blue Na Citrate, 3.2% - fill to fill line on tube |
| Collection Instructions: | If the patient's hematocrit is >55%, contact laboratory to obtain a special tube. If using a butterfly needle, a waste tube must be collected before the blue top tube. |
| After Care: | If the patient has a coagulation abnormality, apply direct pressure to the puncture site for 10 minutes; apply a pressure dressing. Instruct the patient to leave the bandage on for 12 hours. |
| Causes for Rejection: | Underfilled tubes, overfilled tubes, clotted specimens, specimen collected in 3.8% buffered citrate. Whole blood specimen greater than 2 hours old, or not processed appropriately within 1 hour of collection. |
Processing and Shipping
| Specimen Processing: | Must be processed within 1 hour of collection. See Associated Links for additional processing instructions. |
| Shipping Instructions: | Ship processed plasma on dry ice. Must arrive within 48 hours. |
| Test Performed at or Referral Lab | Coagulation (Range, UMMC-East Bank, Lakes, Ridges, Northland, Southdale, UMMC/UMMCH-West Bank, Grand Itasca, St. Joseph's, St. John's, Woodwinds) |
Interpretive
| Critical Range: | >1.10 IU/mL |
| Therapeutic Range: | If collected 4-6 hours after administration:
0.25-0.50 IU/mL for low intensity dosing; 0.30-0.70 IU/mL for high intensity dosing for DVT and PE. |
| Use: | Estimate the concentration of physiologically active heparin anticoagulant (anti-Factor Xa activity) in plasma. |
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