Low Molecular Weight Heparin Anti Xa Level
| Abbrev Code: | ALMWH | ||
| Order Code: | LAB8133 | Order Name: | Low Molecular Weight Heparin Anti Xa Level |
| Synonyms: | Lovenox Anti Xa Level; Enoxoparin Anti Xa Level; Anti Xa Level; Anti 10A Level; Heparin 10A Level; Heparin Xa Level; Anti Xa Level LMWH; Anti 10A Level LMWH; 10 Level Low Molecular Weight Heparin Anti Xa Level | ||
| Methodology: | Chromogenic (synthetic substrate) activity assay | ||
| CPT Codes: | 85520 x1 | ||
| Turnaround Time: | Performed and reported 24 hours/day. | ||
| Associated Links: | Specimen Collection and Processing for Coagulation Specimens |
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Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2.7 mL (in 3 mL tube) - filled to fill line on the tube |
| Minimum\Peds Volume: | 1.8 mL (in 2 mL tube) - filled to fill line on the tube |
| Container: | Blue Na Citrate, 3.2% - fill to fill line on tube |
| Collection Instructions: | If the patient's hematocrit is >55%, contact laboratory to obtain a special tube. If using a butterfly needle, a waste tube must be collected before the blue top tube. |
| After Care: | If the patient has a coagulation abnormality, apply direct pressure to the puncture site for 10 minutes; apply a pressure dressing. Instruct the patient to leave the bandage on for 12 hours. |
| Causes for Rejection: | Underfilled tubes, overfilled tubes, clotted specimens, specimen collected in 3.8% buffered citrate. Whole blood specimen greater than 2 hours old, or not processed appropriately within 1 hour of collection. |
Processing and Shipping
| Specimen Processing: | Must be processed within 1 hour of collection. See Associated Links for additional processing instructions. |
| Shipping Instructions: | Ship processed plasma on dry ice. Must arrive within 48 hours. |
| Test Performed at or Referral Lab | Coagulation (Grand Itasca, Lakes, Northland, Range, Ridges, Southdale, UMMC East Bank, UMMC/UMMCH-West Bank, Woodwinds) |
Interpretive
| Critical Range: | >2.00 IU/mL |
| Therapeutic Range: | If collected 4-6 hours after administration:
Adutls: If administered only once daily with a dose of 1.5 mg/kg: 1.0-2.0 IU/mL. If administered twice daily with a dose of 1 mg/kg: 0.50-1.0 IU/mL. Pediatrics: If administered twice daily: 0.50-1.0 IU/mL. |
| Use: | Quantitative determination of the plasma levels of low molecular weight (LMWH) heparin by measuring the anti-Xa activity on antithrombin in a competitive assay using a synthetic chromogenic substrate. |
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