BK Virus IgG Antibody
| Abbrev Code: | BKVIGG | ||
| Order Code: | LAB8240 | Order Name: | BK Virus IgG Antibody |
| Synonyms: | BKIGG | ||
| Methodology: | Indirect enzyme linked immunosorbent assay (ELISA) | ||
| CPT Codes: | 86790 x | ||
| Turnaround Time: | Specimens are sent to the reference laboratory Mon-Fri; results are reported within1-7 business days. | ||
| Special Instructions: | A Viracor Eurofins test requisition must accompany each specimen. Room temperature specimens must arrive at testing location within 96 hours of collection. | ||
| Compliance: | This test has not been cleared or approved by the US Food and Drug Administration. |
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Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 4 mL |
| Minimum\Peds Volume: | 0.5 mL |
| Container: | Red (no gel) Alternate Containers: Purple (EDTA) |
| Causes for Rejection: | Specimens beyond their acceptable length of time from collection as indicated in the specimen processing section, or specimen types other than those listed. |
Processing and Shipping
| Specimen Processing: | Centrifuge and aliquot 2 mL, 0.2 mL minimum. Store frozen or at room temperature. Room temperature specimens must arrive at the testing location within 96 hours of collection. |
| Shipping Instructions: | Ship overnight at room temperature or frozen. Friday shipments must be labeled for Saturday delivery. |
| Stability: | Specimens are stable for 96 hours at room temperature and indefinitely frozen. |
| Test Performed at or Referral Lab | Lab Sendouts (ViraCor) |
| Referral Lab number: | 2310 (serum); 2301 (EDTA plasma) |
Interpretive
| Reference Range: | Reference range by report.
Results: Antibody titers from <40 to >163840. Test results are reported as an antibody titer, which is the inverse of the specimen dilution that produces signal greater than the assay background level (e.g., 1:2560 specimen dilution is reported as 2560). |
| Use: | Determining the level of anti-BKV IgG antibodies in both kidney donor and recipient has been reported to be a possible factor in predicting the risk of BK nephropathy, an important cause of allograft dysfunction. Moreover, recent scientific data has shown that BK nephropathy in pediatric kidney recipients is associated with the recipient's BKV seronegativity pre-transplant, indicating a potential need for pre-transplant BKV serological testing. |
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