2,3 Dinor 11 Beta Prostaglandin F2 Alpha, Random Urine


Abbrev Code:23BPR   
Order Code:LAB2027Order Name:2,3 Dinor 11 Beta Prostaglandin F2 Alpha, Random Urine
Methodology:Liquid chromatography/Tandem mass spectrometry, enzymatic colorimetric assay
CPT Codes: 84150 x1, 83570 x1
Turnaround Time:Specimens are sent to the reference laboratory Mon-Fri; results are reported within 2-6 days.
Special Instructions:Although a random urine collection is acceptable, the preferred specimen for 2,3-dinor-11beta-prostaglandin F2 alpha analysis is a 24 hour urine collection.
Compliance:

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

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Urine Collection Procedure



Collection Instructions

Specimen:Urine, random
Optimal Volume:Submit entire collection; analysis requires 4 mL.
Minimum\Peds Volume:4 mL
Container:Plastic leakproof container, sterile
Patient Preparation:Patients taking aspirin or nonsteroidal anti-inflammatory drugs (NSAID) may have decreased concentrations of prostaglandin F2 alpha. If possible, discontinue for 2 weeks or 72 hours, respectively, prior to collecting a specimen.
Causes for Rejection:Room temperature specimens. All specimens will be evaluated at Mayo Clinic Labortories for test suitability.


Processing and Shipping

Specimen Processing:Aliquot 5 mL, 4 mL minimum and indicate specimen source on aliquot container. Store refrigerated (preferred).
Shipping Instructions:Ship refrigerated.
Stability:8 hours at room temperature; 14 days refrigerated (preferred); 30 days frozen.
Test Performed at or Referral Lab Lab Sendouts  (Mayo Medical Laboratories)
Referral Lab number:23BPR


Interpretive

Reference Range:Less than 1802 pg/mg creatinine
Limitations:Elevated levels of 2,3-dinor-11beta-prostaglandin F2 alpha (2,3 BPG) in urine are not specific for systemic mast cell disease and may be found in patients with angioedema, diffuse urticaria, or meyloproliferative diseases in the absence of diffuse mast cell proliferation.
Use:Screening for mast cell activation disorders including systemic mastocytosis using random urine specimens.


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