2,3 Dinor 11 Beta Prostaglandin F2 Alpha, Random Urine
| Abbrev Code: | 23BPR | ||
| Order Code: | LAB2027 | Order Name: | 2,3 Dinor 11 Beta Prostaglandin F2 Alpha, Random Urine |
| Methodology: | Liquid chromatography/Tandem mass spectrometry, enzymatic colorimetric assay | ||
| CPT Codes: | 84150 x1, 83570 x1 | ||
| Turnaround Time: | Specimens are sent to the reference laboratory Mon-Fri; results are reported within 2-6 days. | ||
| Special Instructions: | Although a random urine collection is acceptable, the preferred specimen for 2,3-dinor-11beta-prostaglandin F2 alpha analysis is a 24 hour urine collection. | ||
| Compliance: | This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration. |
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Collection Instructions
| Specimen: | Urine, random |
| Optimal Volume: | Submit entire collection; analysis requires 5 mL. |
| Minimum\Peds Volume: | 4 mL |
| Container: | Plastic leakproof container, sterile |
| Patient Preparation: | Patients taking aspirin or nonsteroidal anti-inflammatory drugs (NSAID) may have decreased concentrations of prostaglandin F2 alpha. If possible, discontinue for 2 weeks or 72 hours, respectively, prior to collecting a specimen. |
| Causes for Rejection: | Room temperature specimens. All specimens will be evaluated at Mayo Clinic Laboratories for test suitability. |
Processing and Shipping
| Specimen Processing: | Aliquot 5 mL, 4 mL minimum and indicate specimen source on aliquot container. Store refrigerated (preferred). |
| Shipping Instructions: | Ship refrigerated. |
| Stability: | 8 hours at room temperature; 14 days refrigerated (preferred); 30 days frozen. |
| Test Performed at or Referral Lab | Lab Sendouts (Mayo Medical Laboratories) |
| Referral Lab number: | 23BPR |
Interpretive
| Reference Range: | Less than 1802 pg/mg creatinine |
| Limitations: | Elevated levels of 2,3-dinor-11beta-prostaglandin F2 alpha (2,3 BPG) in urine are not specific for systemic mast cell disease and may be found in patients with angioedema, diffuse urticaria, or myeloproliferative diseases in the absence of diffuse mast cell proliferation. |
| Use: | Screening for mast cell activation disorders including systemic mastocytosis using random urine specimens. |
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