Maternal Serum Screen, First Trimester, hCG, PAPP-A, NT


Abbrev Code:ARMISC   
Order Code:LAB4909Order Name:Laboratory Miscellaneous Orders
Synonyms:Maternal Serum Testing Patient History; Downs Syndrome, First Trimester Screen
Methodology:Quantitative chemiluminescent immunoassay
CPT Codes: 81508 x1
Test Includes:This test does not screen for Open Neural Tube Defect (ONTD). This test is used to screen for fetal risk of Down Syndrome (trisomy 21) and trisomy 18.
Turnaround Time:Specimens are sent to the reference laboratory Mon-Sun; results are reported within 3-5 days.
Special Instructions:Submit with Order: Patient's date of birth, current weight, number of fetuses present, patient's race, if the patient has had previous pregnancy with trisomy, if the patient is currently smoking, if this is a repeat sample, and the age of the egg donor if in vitro fertilization.

In addition to the above: the date of ultrasound, the CRL measurement, the nuchal translucency (NT) measurement, and the name and certification number of the sonographer is required.

NT must be measured when the CRL is between 38-83.9 mm.

The NT measurement must also be performed by an ultrasonographer that is certified by one of the following agencies: Fetal Medicine Foundation (FMF), or Nuchal Translucency Quality Review (NTQR). To avoid possible test delays for an ultrasonographer that is new to our database, please contact the genetic counselfor at (800) 242-2787 extensio 2141 prior to sending the specimen.

If an NT is unobtainable, order Maternal Serum Screening, Integrated (ARUP 3000147 - collect in first trimester) and 3000149 (collect in second trimester), which can be interpreted without an NT value.
Associated Links:

Genetic Testing Consent Form, Maternal Serum Testing Patient History



Collection Instructions

Specimen:Blood
Optimal Volume:6 mL
Minimum\Peds Volume:2.2 mL
Container:Red or gold (gel)
Alternate Containers: Red (no gel)
Collection Instructions:Specimen must be drawn between 11 weeks, 0 days and 13 weeks, 6 days gestation. (Crown-Rump Length [CRL] must be between 43-83.9 mm at the time of specimen collection).
Causes for Rejection:Plasma; hemolyzed specimens.


Processing and Shipping

Specimen Processing:Within 2 hours of collection, centrifuge and aliquot 3 mL, 1 mL minimum. Store refrigerated.
Shipping Instructions:Ship at refrigerated temperature.
Stability:72 hours at room temperature; 2 weeks refrigerated; 1 year frozen. Avoid repeated freeze/thaw cycles.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:3000145


Interpretive

Reference Range:By report.


Click HERE to Report test errors or omissions.
*If no email program is associated with this computer, please contact:
systemlabguide@fairview.org for TestID: 6993"