Chromium and Cobalt, Metal-on-Metal (MoM) Implants, Serum or Plasma

Abbrev Code:Labcorp Misc   
Order Code:LAB4909Order Name:Laboratory Miscellaneous Order
Synonyms:Co; Cr; MOM Implants; 60747 Medtox
Methodology:Inductively coupled plasma/mass spectrometry (ICP/MS)
CPT Codes: 82495 x1, 83018 x1

Collection Instructions

Optimal Volume:2 mL
Minimum\Peds Volume:1.2 mL
Container:Trace Element, Serum (DB)
Alternate Containers: Trace Element, EDTA (DE)

Processing and Shipping

Specimen Processing:Centrifuge and aliquot 2 mL, 0.5 mL minimum, serum or EDTA plasma into a metal-free transport tube. Store refrigerated.
Shipping Instructions:For storage beyond three days, specimen should be refrigerated or frozen.
Stability:<3 days at room temperature. For storage beyond 3 days, specimen should be refrigerated or frozen.
Test Performed at or Referral Lab Lab Sendouts  (LabCorp)
Referral Lab number:738774


Reference Range:Reference range is for patients with metal-on-metal (MoM) orthopedic implants. The American Association of Hip and Knee Surgeons, the American Academy of Orthopaedic Surgeons, and The Hip Society, have published a consensus statement, "Risk Stratification Algorithm for Management of Patients with Metal-on-Metal Hip Arthroplasty." The algorithm is intended as an aid to orthopedic surgeons in the assessment and management of patients with Metal-on-Metal bearings. The systematic risk stratification includes recommendations for multiple modes of failure and stratifies patient risk groups based on a thorough clinical history, a detailed physical examination, radiographic tests, and laboratory tests including measurement of metal ions (chromium and cobalt). The following stratification applies to chromium or cobalt as individual analytes, not to the combined total. Low Risk Group: <3.0 ng/mL; Moderate Risk Group: 3.0 - 10.0 ng/mL; High Risk Group: >10.0 ng/mL. Metal ion tests are an important adjunct to systemic clinical assessment; however, metal ion levels alone should not be relied on as the sole parameter to determine clinical recommendations for revision surgery. J Bone Joint Surg Am. 2014;96:e4(1-6).
Use:Detect metal ion accumulation caused by metal-on-metal (MoM) implants.

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