Chlamydia Antibody Panel, IgG and IgM by IFA


Sunquest Code:ARMISC  
Epic Code:LAB4909Epic Name:IP Lab Panel Chlamydia Antibodies IgG IgM Panel
Order Instructions:Epic SmartGroup order codes: Outpatient: O4046000015 Inpatient: 3046000015 Code orders Chlamydia Antibody Panel, IgG by IFA and Chlamydia Antibody Panel, IgM by IFA
Synonyms:Psittacosis serology
Methodology:Indirect fluorescent antibody
Test Includes:IgG and IgM testing for C. pneumoniae, C. psittaci, and 9 serotypes of C. trachomatis. The LGV strains of C. trachomatis are not included in this assay.
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported in 1-4 days.
Special Instructions:Parallel testing is preferred. Label samples as acute or convalescent.
Compliance:

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the U.S. Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.



Collection Instructions

Specimen:Blood
Optimal Volume:2 mL
Minimum\Peds Volume:0.5 mL
Container:Red (no gel) (Red or gold (gel))
Causes for Rejection:Hemolyzed or lipemic specimens


Processing and Shipping

Specimen Processing:Separate serum from cells ASAP. Centrifuge and aliquot 1 mL, 0.15 mL minimum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:65100


Interpretive

Reference Range:

 

IgG titer

C. trachomatis

Less than 1:64=Not detected

C. pneumoniae

Less than 1:64=Not detected

C. psittaci

Less than 1:64=Not detected

Any IgG titer may indicate past exposure to that particular species. When seen, cross-reactive antibody or the presence of non-specifically stimulated chlamydial IgG antibody is typically less than 128. Infection with a particular chlamydial species typically yields antibody titers which are higher than antibody titers to the non-infecting species. IgG titers in recently infected individuals are typically greater than 512.

 

 

IgM titer

C. trachomatis

Less than 1:20=Not detected

C. pneumoniae

Less than 1:20=Not detected

C. psittaci

Less than 1:20=Not detected

IgM response normally occurs 7-14 days after onset of disease. Low levels of IgM may occasionally persist for more than 12 months post-infection or immunization. Residual IgM response may be distinguished from early IgM response to infection by testing sera from patients 2-3 weeks later for changing levels. Chlamydial IgM antibody is very cross-reactive and will often represent titers to multiple species.

 

 



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