Cyclosporine
| Sunquest Code: | CYC | ||
| Epic Code: | LAB874 | Epic Name: | Cyclosporine |
| Synonyms: | Cyclosporine A; Sandimmune, Neoral; Gengraf; CSA | ||
| Methodology: | Liquid chromatography/tandem mass spectrometry | ||
| Turnaround Time: | Performed and reported daily if received in Drug Analysis by 9:30 am. For levels outside of this time frame, contact Drug Analysis at 612-273-5838. | ||
| Special Instructions: | Comment last dose information. | ||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2 mL |
| Minimum\Peds Volume: | 0.4 mL |
| Container: | Purple (EDTA) (Green (lithium heparin, no gel), Green (sodium heparin, no gel)) |
| Collection Instructions: | Pause and clamp drip for 15 minutes prior to obtaining level. Document stop/start time on MAR.
Usual sampling time is immediately prior to next dose. Analysis should be performed on trough samples (collected no sooner than 2 hours before the dose) unless a kinetic study is ordered. |
| Causes for Rejection: | Collection in gel container; clotted specimen. |
Processing and Shipping
| Specimen Processing: | Do not process whole blood. May be stored at room temperature or refrigerated. |
| Shipping Instructions: | Ship at room temperature.
UMMC West Bank only: Send STAT. |
| Stability: | Do not cancel this test if the specimen is frozen, comment "specimen frozen" when test requesting. |
| Test Performed at or Referral Lab | Drug Analysis (UMMC-East Bank) |
Interpretive
| Critical Range: | Greater than 400 ug/L | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Therapeutic Range: |
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| Use: | Therapeutic drug monitoring and assess toxicity. |
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