Periodic Acid Schiff Stain
| Order Instructions: | Must be ordered by a pathologist. | ||
| Synonyms: | Bone Marrow Cytochemistry and Histochemistry; Cytochemistry Leukocyte; Leukocyte Cytochemistry and Histochemistry | ||
| Methodology: | Aldehyde groups in glycogen stain bright fuchsia pink with leukofuchsin (Schiff reagent) | ||
| CPT Codes: | 88313 x1, 88313 x1, 8831326-26 x1, 88313-26 x1 | ||
| Test Includes: | Periodic Acid Schiff Stain, Blood/Bone Marrow. If requested, interpretation by pathologist is performed at an additional charge. | ||
| Turnaround Time: | Performed Mon-Fri. Results are available within 24 hours. | ||
| Special Instructions: | If an interpretation is not requested, slides will be returned to the sender. | ||
Collection Instructions
| Specimen: | Blood smears, bone marrow smears or imprints |
| Container: | Microscope slides |
| Collection Instructions: | Provide 3-4 unstained blood smears (prepared from fresh blood or EDTA sample), bone marrow smears or imprints. |
Processing and Shipping
| Specimen Processing: | Store at room temperature. |
| Shipping Instructions: | Ship slides in protective slide holder at room temperature. |
| Test Performed at or Referral Lab | UM Special Hematopathology (P) (Ridges, Southdale) |
Interpretive
| Reference Range: | Interpretive report by hematopathologist upon request. |
| Use: | In hematology, this stain has primary value in the diagnosis of erythroleukemia in which it is usually positive in the developing erythroid cells. A positive reaction in acute leukemia favors a lymphocytic differentiation as opposed to myeloid. |
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